Cutaneous Halo Nevi Following Plaque Radiotherapy for Uveal Melanoma

Archives of Opthalmology

Ahmet M. Sarici, Sanket U. Shah, Carol L. Shields, Richard H. Birdsong, Jerry A. Shields

129(11): 1499-1501 November 2011

Halo nevi have been described in both dermatology and ophthalmology.1-2 Cutaneous halo nevi are found more often in children than adults and are believed to result from an immune response.3 Choroidal halo nevus represents 5% of all choroidal nevi and displays low risk for transformation to melanoma.4 The development of cutaneous halo nevi or vitiligo in adulthood can occur following treatment of cutaneous melanoma and correlates with decreased morbidity, presumably due to activation of a systemic immune response.5 There have been rare reports of vitiligo and/or cutaneous halo nevi development following enucleation for uveal melanoma.6-7 A comprehensive study on choroidal halo nevi found a statistical association with history of skin melanoma.2 Herein, we describe a young woman with uveal melanoma who developed a halo ring around numerous pigmented cutaneous nevi . . .

  • <<
  • >>