Clinical Notes: Rat Data Suggest Eye Risk For CF Drug

Monday, September 3, 2012

MedPage Today

Cataracts developed in young rats treated with the cystic fibrosis drug ivacaftor (Kalydeco), prompting the FDA to order a label change. Also this week: a fatal viral infection stalks Yosemite Park.

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The following is a photograph after fluorescein staining of a 40 year old patient with complaints of gritty sensation OU for the past several months. All of the following might be expected except:
1. increased tear break-up time
2. decreased tear meniscus
3. 5mm Schirmer test
4. filamentary keratitis
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Clinical Notes: Rat Data Suggest Eye Risk For CF Drug

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The following is a photograph after fluorescein staining of a 40 year old patient with complaints of gritty sensation OU for the past several months. All of the following might be expected except:

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