An international team of researchers from Queen’s University Belfast, University College London and the University of Alabama at Birmingham have developed a cell culture model they believe could help develop earlier treatment strategies for age-related macular degeneration (AMD).
Through their study, researchers reportedly found retinal pigment epithelial (RPE) cells removed directly from the eye can reproduce all the major known elements of drusen when the cells are grown on specific surfaces. Through their cell culture model, the research team was able to confirm that RPE cells in early AMD are functional and conditions of Bruch's membrane is key for the formation of drusen deposits.
Researchers believe their model provides a new way of looking at how drusen forms, and they reportedly now believe drusen reduction is a viable treatment goal. They reportedly plan to use the cell culture model to uncover the best route to early treatment of AMD before vision loss occurs.
The research was recently published in the journal Investigative Ophthalmology and Visual Science.
Click here to read the full press release.
Like what you read? Follow OphthalmologyWeb to keep up with our latest articles, news and events. Plus, get special offers and more delivered to your inbox.
Source: Queen's University Belfast