Which of the following is NOT a typical sign of thyroid eye disease?

  1. proptosis
  2. ptosis
  3. lid retraction
  4. lid lag

Correct Answer: ptosis

Ptosis is not generally seen in patients with thyroid eye disease. It can rarely be seen in patients with concommitant myasthenia gravis, as seen in less than 1% of patients with Graves disease. Eyelid retraction is the most common sign of thyroid eye disease and is seen in approximately 90% of patients at some point in their clinical course. The most common cause for unilateral or bilateral proptosis is Graves ophthalmopathy. Proptosis is seen in approximately 60% of patients. Lid lag is also a common feature of the disease, present in about 50% of patients.

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