All of the following are true of primary Sjogren Syndrome except:

  1. Most commonly found in elderly males
  2. No associated connective tissue disease
  3. 90% HLA-B8 haplotype +
  4. Associated with anti-La (SS-B) autoantibodies

Correct Answer: Most commonly found in elderly males

Primary Sjogren Syndrome is found in a homogeneous group of young to middle age women. Unlike secondary Sjogren Syndrome, primary is not associated with known connective tissue disorders.

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