OPKO Health Initiates Clinical Trial Of The Aquashunt(TM) To Treat Glaucoma

BUSINESS WIRE

MIAMI, Jan 22, 2009 (BUSINESS WIRE) -- OPKO Health, Inc. (AMEX:OPK) announced today that it has begun treating patients in a clinical trial of its Aquashunt(TM), a device for the treatment of refractory open angle glaucoma. The study, at two academic departments of ophthalmology, is designed to assess the safety and efficacy of the Aquashunt(TM) and will enroll up to 20 patients with significantly impaired visual acuity.

The Aquashunt(TM) is a novel device designed to lower intraocular pressure by allowing excess fluid in the eye to exit more naturally than occurs with presently available devices.

"We are pleased by the simplicity of the surgical procedure for the device and by the early results in the first human trials," commented Bruce Shields, M.D., Professor of Ophthalmology at Yale University and designer of the Aquashunt(TM). "These early results provide further validation of our optimism for the future of the Aquashunt(TM), and we look forward to completing our clinical trials and bringing this product to market."

About Glaucoma

Glaucoma occurs when fluid accumulating in the eye raises the intraocular pressure and causes the optic nerve to degenerate, potentially leading to irreversible vision loss. Glaucoma is increasing in prevalence as the population ages, currently affecting an estimated 2.4 million people in the U.S. and about 60 million people worldwide.

It is the leading cause of bilateral, irreversible blindness.

About OPKO Health, Inc.

Miami-based OPKO is a specialty healthcare company engaged in the development, marketing, and sales of novel agents and both diagnostic and therapeutic devices for the management of ophthalmic diseases. For more information visit the company's website at www.opko.com.

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