Which of the following is false regarding the development of diabetic retinopathy?

  1. The earliest vascular abnormality is the loss of retinal capillary intramural pericytes.
  2. Microaneurysm formation is the earliest clinical sign of diabetic retinopathy.
  3. Microaneurysm formation typically occurs on the arteriolar side of the retinal vasculature.
  4. Basement membrane thickening is histopathologically evident in diabetes.

Correct Answer: Microaneurysm formation typically occurs on the arteriolar side of the retinal vasculature.

Microaneurysm formation is typically on the venular side of the retinal vasculature.

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