Carbonic Anhydrase Inhibitors

CompanyMerck & Co., Inc.Merck & Co., Inc.
ItemCosoptTrusopt
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DescriptionCOSOPT (dorzolamide hydrochloride-timolol maleate ophthalmic solution) is the combination of a topical carbonic anhydrase inhibitor and a topical beta-adrenergic receptor blocking agent.TRUSOPT (dorzolamide hydrochloride ophthalmic solution) is a carbonic anhydrase inhibitor formulated for topical ophthalmic use.
Size5 mL, 10 mL5 mL, 10 mL
IndicationCOSOPT is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time). The IOP-lowering of COSOPT b.i.d. was slightly less than that seen with the concomitant administration of 0.5% timolol b.i.d. and 2.0% dorzolamide t.i.d.TRUSOPT Ophthalmic Solution is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
StorageStore COSOPT at 15 - 30° C (59 - 86° F). Protect from light.Store TRUSOPT Ophthalmic Solution at 15 - 30° C (59 - 86° F). Protect from light.
How SuppliedSolution2% Solution
Generic NameTimolol Maleate / DorzolamideDorzolamide
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