Keratoprosthesis

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AlphaCor™ Artificial Cornea

AlphaCor™ Artificial Cornea

Addition Technology, Inc.

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  • Features: Design:
    AlphaCor is a one piece convex disc consisting of a central transparent optic and an outer skirt that is entirely manufactured from poly (2 – hydroxyethyl methacrylate) or PHEMA. AlphaCor’s material and patented features are designed to promote retention and optimize patient outcomes.

    Outer Skirt:
    The outer skirt is an opaque, high water content, PHEMA sponge. The porosity of the sponge encourages biointegration with host tissue and thus promotes retention of the implanted device.

    Central Optic:
    The central optic core is a transparent PHEMA gel providing a refractive power similar to that of the human cornea. The optic core is designed to allow the patients’ visual potential to be achieved.

    The Interpenetrating Polymer Network (IPN):
    The junctional zone between the skirt and central optic is the Interpenetrating Polymer Network or IPN. This is a permanent bond formed at the molecular level and is designed to prevent the down-growth of cells around the optic, which can lead to the formation of retroprosthetic membranes, one of the major complications historically associated with artificial corneas.
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Boston Keratoprosthesis

Boston Keratoprosthesis

Massachusetts Eye & Ear Infirmary

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  • Features: Indications:
    • Two failed grafts, with poor prognosis for further grafting,
    • Vision less than 20/400 in the affected eye and additionally with lower than optimal vision in the opposite eye,
    • No end-stage glaucoma or retinal detachment.
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OCULAID® Keratoprosthesis

OCULAID® Keratoprosthesis

OPHTEC BV

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  • Features:
    • The cornea should merely act as a host to the KP, with minimal participation in preventing its extrusion.
    • The steel suture fixation on the aequatorial sclera take care of preventing extrusion
    • The "pressure from behind" prevents:
      • Leaking of aequeous humor between the KP and the cornea.
      • Melting away of corneal tissue around the KP.
      • Penetration of superficial infection.
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