All of the following diagnoses are associated with cystoid macular edema (CME) on clinical examination and are also not with associated macular leakage on fluorescein angiography except for which one?

  1. Nicotinic acid maculopathy
  2. Idiopathic juxtafoveal (parafoveal) retinal telangiectasis (IJRT)
  3. Goldman Favre Syndrome
  4. Juvenile X-linked Retinoschisis
  5. Enhanced S-cone dystrophy

Correct Answer: Idiopathic juxtafoveal (parafoveal) retinal telangiectasis (IJRT)

Fluorescein leakage is typically observed in the temporal macula in IJRT, but fluorescein leakage is typically absent in all the other conditions despite observation of macular edema on clinical exam. This is often the case in some forms of epiretinal membrane and vitreomacular traction syndrome as well.

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