Causes of aqueous tear deficiency include all of the following except:

  1. Riley-Day Syndrome
  2. Anhidrotic Ectodermal Dysplasia
  3. Shy-Drager Syndrome
  4. Fraser Syndrome

Correct Answer: Fraser Syndrome

Riley-Day Syndrome (familial dysautonomia) is a congenital syndrome associated with ATD. As well, Shy-Drager Syndrome (idiopathic autonomic dysfunction) is associated with ATD. Fraser Syndrome is not associated with ATD but rather includes cryptophthalmos, renal agenesis and anal atresia.

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