Researchers at Salk Institute were recently able to use a new gene-editing technology to partially restore visual responses in blind rodents, opening new avenues for basic research and a variety of treatments for retinal diseases and others.
Using this new technology, researchers were reportedly able for the first time to insert a new gene into a precise DNA location in adult cells that no longer divide, such as those of the eye, offering new possibilities for therapeutic applications in these cells. During their study, the research team tested their new technique on a rat model for retinitis pigmentosa. Upon completion of the gene-replacement therapy, the animals were reportedly able to respond to light and passed several tests indicating healing in their retinal cells.
The study was recently published in the journal Nature.
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